Pei-Yong Shi Selected Research

Viremia

11/2020	A Cyclic Phosphoramidate Prodrug of 2'-Deoxy-2'-Fluoro-2'-C-Methylguanosine for the Treatment of Dengue Virus Infection.
1/2020	A replication-defective Japanese encephalitis virus (JEV) vaccine candidate with NS1 deletion confers dual protection against JEV and West Nile virus in mice.
1/2020	Vesicular Stomatitis Virus and DNA Vaccines Expressing Zika Virus Nonstructural Protein 1 Induce Substantial but Not Sterilizing Protection against Zika Virus Infection.
1/2020	A Zika virus envelope mutation preceding the 2015 epidemic enhances virulence and fitness for transmission.
10/2017	Evaluation of a Novel Reporter Virus Neutralization Test for Serological Diagnosis of Zika and Dengue Virus Infection.
6/2017	A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models.
10/2016	Characterization of a 2016 Clinical Isolate of Zika Virus in Non-human Primates.
10/2016	Therapeutic Potential of Spirooxindoles as Antiviral Agents.
2/2014	Activation of peripheral blood mononuclear cells by dengue virus infection depotentiates balapiravir.
1/2011	Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo.

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Pei-Yong Shi Research Topics

Disease

82	Infections 01/2024 - 09/2003
60	COVID-19 03/2024 - 01/2020
41	Dengue (Dengue Fever) 12/2023 - 09/2003
31	Virus Diseases (Viral Diseases) 12/2023 - 02/2005
20	Zika Virus Infection 08/2023 - 12/2016
12	Viremia 11/2020 - 12/2009
11	Flavivirus Infections 11/2022 - 01/2006
9	Inflammation (Inflammations) 04/2023 - 10/2014
8	Yellow Fever 01/2023 - 03/2006
8	West Nile Fever 01/2017 - 09/2003
5	Vesicular Stomatitis 07/2021 - 02/2009
4	Communicable Diseases (Infectious Diseases) 01/2023 - 01/2015
4	Glioblastoma (Glioblastoma Multiforme) 11/2021 - 10/2017
3	Neoplasms (Cancer) 01/2023 - 01/2018
3	Fever (Fevers) 01/2023 - 01/2016
3	Weight Loss (Weight Reduction) 10/2021 - 01/2021
3	Body Weight (Weight, Body) 01/2020 - 08/2010
3	Congenital Abnormalities (Deformity) 01/2018 - 01/2017
2	Lymphopenia (Lymphocytopenia) 03/2024 - 10/2014
2	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2024 - 01/2024
2	Post-Acute COVID-19 Syndrome 01/2024 - 01/2024
2	Neuroinflammatory Diseases 01/2024 - 10/2015
2	Human Influenza (Influenza) 01/2023 - 01/2022
2	Coronavirus Infections 01/2022 - 06/2021
2	Weight Gain 01/2022 - 06/2021
2	Pneumonia (Pneumonitis) 11/2021 - 11/2020
2	Severe Acute Respiratory Syndrome 01/2021 - 10/2020
2	Disease Progression 12/2020 - 10/2015
2	Encephalitis (Encephalitis, Rasmussen) 01/2020 - 10/2015
2	Guillain-Barre Syndrome 10/2019 - 12/2016
2	Japanese Encephalitis 11/2018 - 01/2018
2	Microcephaly 11/2017 - 12/2016
2	Superinfection 09/2014 - 11/2009

Drug/Important Bio-Agent (IBA)

63	VaccinesIBA 01/2024 - 12/2009
48	Antiviral Agents (Antivirals)IBA 01/2023 - 03/2006
42	Proteins (Proteins, Gene)FDA Link 03/2024 - 09/2003
22	Neutralizing AntibodiesIBA 01/2024 - 02/2014
20	RNA (Ribonucleic Acid)IBA 12/2023 - 04/2005
18	AntibodiesIBA 01/2023 - 07/2006
16	Viral RNAIBA 01/2024 - 04/2006
9	NucleosidesIBA 01/2022 - 12/2009
8	BNT162 VaccineIBA 04/2023 - 10/2020
7	mRNA VaccinesIBA 12/2023 - 10/2020
7	CytokinesIBA 01/2023 - 07/2009
7	ProdrugsIBA 01/2022 - 08/2010
7	InterferonsIBA 01/2021 - 02/2005
6	Immunoglobulin G (IgG)IBA 10/2023 - 01/2019
5	remdesivirIBA 01/2023 - 01/2021
5	EnzymesIBA 10/2022 - 11/2012
4	Immunoglobulin A (IgA)IBA 10/2023 - 11/2021
4	Interferon Type IIBA 01/2023 - 05/2013
4	Attenuated VaccinesIBA 02/2021 - 01/2018
4	Immunoglobulin M (IgM)IBA 01/2021 - 02/2017
4	Peptide Hydrolases (Proteases)FDA Link 11/2019 - 12/2009
3	Alanine (L-Alanine)FDA Link 03/2022 - 10/2021
3	2019-nCoV Vaccine mRNA-1273IBA 10/2021 - 01/2021
3	triphosphoric acid (triphosphate)IBA 11/2020 - 02/2014
3	Peptides (Polypeptides)IBA 10/2020 - 09/2014
3	3' Untranslated Regions (3' UTR)IBA 04/2020 - 01/2017
3	PolyproteinsIBA 10/2019 - 11/2017
3	DNA-Directed RNA Polymerases (RNA Polymerase)IBA 01/2018 - 12/2009
3	LuciferasesIBA 01/2017 - 04/2006
2	Complement System Proteins (Complement)IBA 01/2024 - 01/2024
2	SphingolipidsIBA 01/2024 - 08/2022
2	COVID-19 VaccinesIBA 10/2023 - 01/2023
2	Monoclonal AntibodiesIBA 01/2023 - 01/2021
2	FurinIBA 01/2023 - 01/2021
2	JIB-04IBA 01/2022 - 06/2021
2	aluminum sulfate (alum)IBA 11/2021 - 11/2021
2	SARS-CoV-2 spike proteinIBA 07/2021 - 02/2021
2	Glycoproteins (Glycoprotein)IBA 03/2021 - 10/2020
2	Complementary DNA (cDNA)IBA 01/2021 - 12/2013
2	Adenosine (Adenocard)FDA LinkGeneric 01/2021 - 10/2015
2	phosphoramidic acidIBA 11/2020 - 01/2018
2	Type I DNA Topoisomerases (Topoisomerase I)IBA 10/2020 - 03/2020
2	DNA (Deoxyribonucleic Acid)IBA 10/2020 - 03/2020
2	Interferon LambdaIBA 01/2020 - 07/2009
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2020 - 11/2018
2	MethyltransferasesIBA 01/2020 - 04/2007
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2018 - 01/2017
2	Viral ProteinsIBA 01/2018 - 10/2014
2	Interferon-betaIBA 01/2017 - 07/2004
2	AntigensIBA 12/2016 - 06/2015
2	NITD008IBA 10/2015 - 12/2009
2	Membrane Proteins (Integral Membrane Proteins)IBA 11/2012 - 08/2010
2	m7GpppAIBA 08/2010 - 04/2007
1	tRNA MethyltransferasesIBA 03/2024
1	ProteomeIBA 03/2024
1	Biomarkers (Surrogate Marker)IBA 03/2024
1	Histone MethyltransferasesIBA 03/2024
1	Immunologic Factors (Immunomodulators)IBA 01/2024
1	N-methyl-valyl-amiclenomycin (BA 2)IBA 12/2023
1	Metformin (Glucophage)FDA LinkGeneric 08/2023
1	ChemokinesIBA 01/2023
1	EpitopesIBA 01/2023

Therapy/Procedure

37	Therapeutics 03/2024 - 01/2006
4	Oral Administration 04/2023 - 01/2011
2	Microspheres (Microsphere) 01/2019 - 07/2006
2	Blood Transfusion (Blood Transfusions) 11/2003 - 09/2003
2	Organ Transplantation 11/2003 - 09/2003